专利摘要:
An orally administrable pharmaceutical dosage unit having a shape such that its most stable position on a horizontal flat surface is a tilted position. This is obtained for instance by providing the main body (11) with one or more projections (12, 13). The units can be made by forming the active ingredient and any excipient into the shape as defined.
公开号:SU1416047A3
申请号:SU823520950
申请日:1982-12-03
公开日:1988-08-07
发明作者:Дейвид Товей Джеффри
申请人:Смит Клайн Энд Фрэнч Лабораториз Лимитед (Фирма);
IPC主号:
专利说明:

2 4
four
o: i o
4ib
 S
city /
The invention relates to the pharmaceutical industry and may be used in the manufacture of dosage forms.
The aim of the invention is the convenience of the shape providing an inclined position relative to the horizontal plane.
FIG. 1 shows the dosage form, a general perspective view; in fig. 2 - the same, side view; in fig. 3 - the same, top view; in fig. 4-63 are embodiments of the dosage form.
The dosage form is a body, the names of the shapes of a triangular prism 1, on opposite sides of which are projections 2 and 3 dome-shaped, located in the center of the triangular face 4 and ensuring the inclination of the body at an angle of 6-40 ° to the horizontal, while the angles 5 which face the body, rounded, and the peripheral edges of the 6 large faces 4 are made with a facet.
The body of the dosage form can be made in the form of a regular parallelepiped 7, having a size ratio of 8 to 9 large faces to a size of 10 smaller 2.5: 1 facets, the projections 11 and 12 are dome-shaped. The corners 13, the connecting large edges 8 and 9, are rounded, and their peripheral edges 14 are chamfered.
The body of the dosage form can be made in the form of a regular parallelepiped 15 having projections 16 and 17 dome-shaped with one face 18.
The body of the dosage form may have projections 19 and 20 dome-shaped with two faces 21 and 22, projections 23 and 24 with three faces 25 on one of the projections or projections 26 and 27 with four faces 28
The dosage form may have a body made in the form of a regular pentagonal prism 29, which on opposite sides of the protrusions 30 and 31 are dome-shaped, located in the center, while the peripheral edges have a chamfer 32.
The dosage form may have a body, shaped like a cylinder 33 with the smallest size 34 and two equal largest sizes 35 and 36, and centrally located protrusions
0
five
0
five
0
five
0
five
0
five
37 and 38 are dome-shaped, while the faces 39 are curved.
The dosage form may have a body having an ellipse 40 in cross section with two projections 41 and 42 located in the center and a chamfer 43 along the periphery.
The dosage form may have a body, shaped as a parallelepiped 44, having protrusions 45 and 46 of a hemispherical shape located on opposite sides near the middle of the opposite short edge, or protrusions 47 and 48 of a hemispherical shape located diagonally in opposite corners.
The dosage form may have a body, made in the form of a parallelepiped 49, having two equal smallest sizes and one largest, while the projections 50 have a hemispherical shape and are located on each large face 51 "
The dosage form may have a capsule-shaped body 52 with four radial protrusions 53 symmetrically located on the surface at one end, with each protrusion ending in a dome.
The dosage form may have a body, made in the form of a cube 54, having dome-shaped projections 55 on each face.
The dosage form may have a body made in the form of a triangular prism 56 having projections representing triangular pyramids 57 and 58.
The dosage form may have a body made in the form of a regular parallelepiped 59 with protrusions, represented by square cells 60 and 61.
The dosage form may have a body that is embodied in the form of a regular pentagonal prism 62 with protrusions that are nugol; pyramids 63 and 64, each of which is located in the center of a large face 65.
The dosage form may have a body made in the form of a ring 66 with two protrusions 67 having a hemispherical shape, with one pair of protrusions located diametrically opposite on one side of the ring 66, and the other opposite of the first on the other side of the ring 66.
The dosage form may have a body, embodied in the form of a parallelepiped with protrusions 68 and 69, having triangles in cross section, located in the middle and along a large face parallel to the largest size of the main body.
The dosage form may have a body, made in the form of a disk 70, having projections 71 and 72 on opposite sides, which are triangles in cross section.
The dosage form may have a body made in the form of a parallelepiped 73, having on opposite sides protrusions representing quadrangular pyramids 74 and 75, while the end faces 76 of the body have a chamfer and rounded corners 77.
The dosage form may have a body that has an elongated cross-section.
one of the protrusions 11 or 12 touches the surface. In this inclined position, the center of gravity of the dosage form is in the lower position.
When vsechache form of container, the body of which is made in the form of a regular pentagonal prism 29, it can fall on the side face or on one of its large faces. If it lies on its side face, it is in an unstable position and can be turned into a stable inclined position (Fig. 19), in which 5 the protrusion 31 touches the surface.
When taken out of a container on a flat surface of the dosage form, the body of which is made in the form of a cylinder 33, it may fall on a side face or on one of the end faces. If it lies on a curved face, it is in an unstable position and can be inverted
lip 78 with located on his pro 25 that in an inclined position (Fig.22)
the protruding sides of the protrusions 79 and 80, having an arcuate shape at the base, and in cross section - a triangle, while the end faces 81 of the housing can have an elliptical shape 82, and the protrusions 83 and 84 of the arcuate shape pass through the center.
The dosage form may have a body that is made in the form of a parallel of the pygmy 85 with a protrusion located along the periphery at one of its ends, which is a comb with a facet on a larger face.
The dosage form is as follows.
Dosage forms are suspended on a flat, horizontal surface. If the dosage form, having the shape of a triangular prism 1, lies on the side face, then it is in an unstable position and can be turned into a stable position (Fig. 2), in which the dome shaped projection 3 is in contact with the surface.
When taken out of a container onto a flat surface of the dosage form, made in the form of parallelepiped 7, it can fall onto one of its small faces, i.e. on the side face. This position is unstable and it can be turned into a stable position (Fig. 6), in which
0
0

thanks to one of the projections 37 and 38. Therefore, due to the presence of projections on the surface of the body, projections take an inclined position on the sun surface, and therefore they can be easily taken.
权利要求:
Claims (15)
[1]
1. Solid oral dosage form, having a body with protrusions on opposite sides, characterized in that, for ease of use, the height of the protrusions is chosen such that it provides a stable oblique position of the body at an angle of 6-40 to the horizontal axis.

[2]
2. Dosage form according to claim 1, characterized in that the protrusion has the shape of a parallelepiped, a cube, a pyramid or a dome.
[3]
3. A dosage form according to claim 1, characterized in that the pyramid is made three-, four-fold or five-sided.
[4]
4. A dosage form according to claim 1, wherein the protrusion has a rounded shape.
[5]
5. A dosage form as defined in claim 2, characterized in that
514
A stupa, made in the form of a dome, has from one to four sides,
[6]
6. A dosage form according to claims 1-5, characterized in that one of the dimensions of the body is larger than the other two.
[7]
7. Dosage form according to claim 6, characterized in that the two remaining body sizes are equal.
[8]
8. Dosage form according to paragraphs. 6 and 7, characterized in that the body is capsule-shaped.
[9]
9. Dosage form according to paragraphs. 7 and 8, characterized in that the ratio of the largest body size to the smallest one is in the range of 2.5: 1-3.5: 1.
[10]
10. Dosage form according to paragraphs. 1-5, characterized in that the housing has two equal sizes and one smaller.
9ag.2
needles
0
60476
[11]
11. A dosage form as defined in claim 10, wherein the housing is in the shape of a cylinder.
[12]
12. The dosage form of claim 11, wherein the ratio of the smallest and largest body sizes is in the range of 1: 2-1: 3.5.
[13]
13. The dosage form according to claim 10, wherein the housing is designed as a parallelepiped.
[14]
14. A dosage form according to claim 13, characterized in that the ratio of the smallest body size
and the largest is in the range of 1: 2-1: 3.5.
[15]
15. Dosage form according to paragraphs. 13 and 14, characterized in that the angles connecting the two largest faces of the parallelepiped are rounded. Priority points;
04.12.80 in paragraphs. 13 and 05.12.80 on p. 15
five
0
14
04/28/81 on PP
five
1-12
ag 3
ig.5
UL8. 6
19 22
 Fig. 9
9g L
 Rig: / J
sixteen
 Heaven 7
ag eight
Z1 W
ag W
ag 12
ag /
fas. 15
J2
(game 17
. nineteen
21
Rav. sixteen
29
 Rig. 18
J
fas. 22
ag 32
3 2
ig. 33
1416047
5J 52
.36
fas. J7
fas. 0
. 39
fae. 2
ag 4J
$ 3
ag 38
faz. one
60
65
 Rig. 44
54
65.
fas. five
69
 Rig. 50
FIG. 51
ig. five
S3
9ag. 6
 Rag. 52
73
75
ig. 55
76
类似技术:
公开号 | 公开日 | 专利标题
SU1416047A3|1988-08-07|Solid medication for oral ingestion
KR880002697B1|1988-12-26|A basketball
Lewis1923|The typical shape of polyhedral cells in vegetable parenchyma and the restoration of that shape following cell division
US4806288A|1989-02-21|Packing elements
RU2001123702A|2003-06-10|Diamond Cut Shape for Jewelry
RU2006139638A|2008-05-20|OVAL DIAMOND DIAMOND
GB2039773A|1980-08-20|Spiral packing element
US5556096A|1996-09-17|Dice
JP2001504509A|2001-04-03|Product
EP0928624B1|2004-02-25|Random number generator for game playing
Bezdek et al.2019|On contact graphs of totally separable domains
GB2111395A|1983-07-06|Manipulative puzzle
Lewis1949|The analogous shapes of cells and bubbles
Apostol et al.2006|Solids circumscribing spheres
JP2599952B2|1997-04-16|Joint piece
US3811683A|1974-05-21|Cube forming disc puzzle
US4647448A|1987-03-03|Pharmaceutical dosage unit
US5203562A|1993-04-20|Dice construction
KR860000498Y1|1986-04-07|Dosage units
KR860000445Y1|1986-03-31|Dosage units
RU2001127929A|2002-04-10|SPHERE-REPLACING POLAHONES
KR200184511Y1|2000-06-01|A pyramid type lid or cover
KR920012948A|1992-07-28|REFLEX REFLECTOR
JPH09140557A|1997-06-03|Vessel placement structure for trivet
Martin1909|ARITHMETIC rid MENSURATION.
同族专利:
公开号 | 公开日
HU191335B|1987-02-27|
DD159395A5|1983-03-09|
JPS57501847A|1982-10-14|
JPH044294B2|1992-01-27|
OA07281A|1984-08-31|
CY1496A|1990-02-16|
EP0055009B1|1986-11-05|
FI78392B|1989-04-28|
ES272449Y|1984-05-16|
AU7130281A|1982-06-10|
SK413381A3|1997-06-04|
IN156458B|1985-08-03|
GR74566B|1984-06-29|
PT73129B|1982-07-15|
DE3175541D1|1986-12-11|
IL63036A|1987-11-30|
FI824486L|1982-12-28|
DK160077C|1991-06-24|
IE52151B1|1987-07-08|
CA1176566A|1984-10-23|
CZ281241B6|1996-07-17|
SK278448B6|1997-06-04|
PT73129A|1981-07-01|
CZ413381A3|1996-07-17|
DK160077B|1991-01-28|
ZW12881A1|1982-04-07|
IL63036D0|1981-09-13|
IE811220L|1982-06-04|
US4493822A|1985-01-15|
EG16613A|1989-09-30|
SG47789G|1989-12-22|
BG60229B2|1994-01-18|
ES272449U|1983-11-16|
ZA813205B|1983-03-30|
DK330482A|1982-07-23|
FI78392C|1989-08-10|
FI824486A0|1982-12-28|
EP0055009A1|1982-06-30|
NZ197287A|1985-07-12|
US4376111A|1983-03-08|
AU550544B2|1986-03-27|
WO1982001818A1|1982-06-10|
HK100089A|1989-12-22|
引用文献:
公开号 | 申请日 | 公开日 | 申请人 | 专利标题

US91644A|1869-06-22|Improvement in roller-cutters for flows |
US582021A|1897-05-04|Karl morstadt |
US60248A|1866-12-04|bobbins |
US202750A|1878-04-23|Improvement in balloons |
US680052A|1901-04-02|1901-08-06|Thomas A Lynch|Soap cake.|
US982711A|1907-10-25|1911-01-24|Ellis Foster Co|Dog-biscuit.|
FR400217A|1909-02-16|1909-07-21|Henry Edmunds|Cookie enhancements for dogs|
GB191504480A|1915-03-22|1915-09-02|Pierre Lannou|Improvements in Soap Tablets.|
US1268470A|1918-01-28|1918-06-04|Charles L Johnson|Device for teething infants.|
FR536439A|1921-06-03|1922-05-03|Parfumerie Millot Sa|Non-slip or non-slip soap from the hand|
US1695567A|1924-03-26|1928-12-18|Ellis Foster Co|Animal food|
GB230333A|1924-06-28|1925-03-12|William James Spicer|Improvements in or relating to baby comforters or soothers|
FR607565A|1925-12-08|1926-07-05|Savonnerie Parfumerie Maubert|Soaps|
US1749632A|1928-05-11|1930-03-04|Henry C Ferris|Orthodontic dumb-bell|
GB321965A|1928-05-23|1929-11-25|Ellis Foster Co|Improvements relating to animal foods|
FR690545A|1930-02-25|1930-09-23|Tokalon|Soap with added part|
USD91644S|1933-12-22|1934-03-06|Alex Blackstone|Design for a proprietary medicine bar|
FR778531A|1934-09-17|1935-03-18|Peripheral streak soap|
US2105690A|1935-06-01|1938-01-18|Carl J Greenblatt|Effervescent tablet|
FR807775A|1936-07-01|1937-01-21|Pharmaceutical stamp|
US2115405A|1936-10-29|1938-04-26|Paul E Allen|Teething device|
US2131229A|1937-09-25|1938-09-27|Harold G Mcmennamin|Dog's plaything|
US2185547A|1938-07-14|1940-01-02|Fowler John|Dog toy|
US2386416A|1943-03-01|1945-10-09|Warren F Wilhelm|Tablet and means for packaging same|
US2420734A|1946-02-04|1947-05-20|Charles H Churchill|Toilet soap novelty|
GB614258A|1946-07-04|1948-12-13|Marjorie Egerton Storey|Improvements relating to teething devices for infants|
US2505444A|1947-02-27|1950-04-25|William Isler|Soap bar|
US2580414A|1948-03-01|1952-01-01|Duffey Thomas Edward|Capsule|
FR1007797A|1948-04-01|1952-05-09|Bar of soap|
US2588812A|1950-06-27|1952-03-11|Sun Oil Co|Wax cake|
US2778045A|1952-10-31|1957-01-22|Bly Isaiah|Dentifrice-containing capsules|
FR1110203A|1954-10-20|1956-02-09|Soap or bar associated with a spongy or fibrous body or horsehair|
US2903365A|1957-01-22|1959-09-08|Edward D O'brian|Confection structures|
GB993291A|1961-12-06|1965-05-26|Thomas Lee Cooper|Tablets, pills, pellets and the like|
GB975333A|1961-12-16|1964-11-18|Charles Walker & Sons Tanners|Dog chews and a method of manufacturing the same|
US3104648A|1962-02-26|1963-09-24|Stanton E Fisher|Animal toy|
US3336200A|1963-05-28|1967-08-15|Warner Lambert Pharmaceutical|Tablet structure|
FI44458B|1963-06-18|1971-08-02|Ucb Sa|
US3374917A|1964-01-09|1968-03-26|Constantine T. Troy|Interlocking structural elements|
US3415225A|1966-11-21|1968-12-10|Farmland Ind|Artificial roughage for ruminants|
US3567459A|1967-07-12|1971-03-02|Philip J Wruk|Simulated bone comprising sugar solids in a molten-thixotropic thermosetting form|
US3532633A|1968-05-29|1970-10-06|Laurel B Withers|Cleanser bars|
DE2019715C3|1970-04-23|1982-02-04|Kessi-Werk Max Messmann Gmbh, 1000 Berlin|Item for playing or eating for pets kept in the home|
GB1346610A|1971-07-02|1974-02-13|
US3882257A|1971-06-21|1975-05-06|Cagle S Inc|Preparation of pet food from bones and animal by-products|
US4032665A|1973-09-10|1977-06-28|Ralston Purina Company|Simulated bone|
US3899607A|1971-08-24|1975-08-12|Ralston Purina Co|Simulated bone|
US3883647A|1972-12-06|1975-05-13|Ives Lab|Tablet formulation|
US4053650A|1973-11-13|1977-10-11|Meji Seika Kaisha Ltd.|Baked confections and process for the preparation thereof|
US3871334A|1973-12-03|1975-03-18|Herbert R Axelrod|Pet toy|
US4260635A|1974-12-18|1981-04-07|Fisher Stanton E|Unitized animal food system product|
US4055178A|1976-03-10|1977-10-25|Harrigan Roy Major|Drug delivery device for preventing contact of undissolved drug with the stomach lining|
USD257365S|1978-05-08|1980-10-14|Matrix Toys|Joint element for construction set|
DE2834226A1|1978-08-04|1980-02-28|Merck Patent Gmbh|Multilayer tabletting system for pharmaceutical prods. - with separate filler spaces and split bottom plunger|
US4215104A|1979-03-26|1980-07-29|Mead Johnson & Company|Multi-fractionable tablet structure|
US4258027A|1979-03-26|1981-03-24|Mead Johnson & Company|Multi-fractionable tablet structure|
ZA813205B|1980-12-05|1983-03-30|Smith Kline French Lab|Dosage units|
CA1201372A|1982-06-24|1986-03-04|Corporation Cadre |Oxygen-fuel burner with lancing capability|ZA813205B|1980-12-05|1983-03-30|Smith Kline French Lab|Dosage units|
CA1195251A|1981-07-20|1985-10-15|Anthony B.J. Eoga|Convex tablet configuration|
US4591500A|1983-04-25|1986-05-27|Microencapsulation S.A.|Tablet having the shape of a capsule, process and device for its preparation|
US4891218A|1985-08-02|1990-01-02|Sherman Daniel A|Rodenticide bait block|
JP2514102B2|1990-06-13|1996-07-10|ユリカ株式会社|Tablet product using a vacuum freeze-dried product of a plant belonging to the genus Aloe of the family Liliaceae and a method for producing the same|
GB9101502D0|1991-01-23|1991-03-06|Controlled Therapeutics Sct|Controlled release compositions|
JP2964195B2|1992-04-28|1999-10-18|エスエス製薬株式会社|Piroxicam tablets and method for producing the same|
US5431918A|1992-10-30|1995-07-11|Soremartec S.A.|Breath mint configuration|
US5662849A|1993-09-10|1997-09-02|Fulsz Technologies Ltd.|Method and apparatus for forming compression dosage units within the product package|
US5648033A|1993-09-10|1997-07-15|Fuisz Technologies Ltd.|Method and apparatus for retaining a formed compression dosage unit within a die cavity|
US5616344A|1994-06-14|1997-04-01|Fuisz Technologies Ltd.|Apparatus and process for strengthening low density compression dosage units and product therefrom|
US5653926A|1993-09-10|1997-08-05|Fuisz Technologies, Ltd.|Method and apparatus for forming compression dosage units|
GB9325644D0|1993-12-15|1994-02-16|Smithkline Beecham Plc|Novel formulation|
USD383534S|1996-03-12|1997-09-09|Smithkline Beecham Corporation|Pharmaceutical tablet|
USD383533S|1996-03-12|1997-09-09|Smithkline Beecham Corporation|Pharmaceutical tablet|
ITFI970184A1|1997-07-30|1999-01-30|Menarini Farma Ind|PHARMACEUTICAL COMPOSITIONS CONTAINING VITAMIN D AND CALCIUM, THEIR PREPARATION AND THERAPEUTIC USE|
USD431676S|1999-10-06|2000-10-03|Benckiser, N.V.|Detergent tablet|
USD434492S|1999-10-08|2000-11-28|Smithkline Beecham Corporation|Six sided pharmaceutical tablet|
JP2005145821A|2003-11-11|2005-06-09|Kao Corp|Tablet preparation|
US7985419B1|2006-12-22|2011-07-26|Watson Laboratories, Inc.|Divisible tablet and associated methods|
US20090087483A1|2007-09-27|2009-04-02|Sison Raymundo A|Oral dosage combination pharmaceutical packaging|
US8439033B2|2007-10-09|2013-05-14|Microdose Therapeutx, Inc.|Inhalation device|
MY154023A|2009-04-22|2015-04-30|Kyowa Chem Ind Co Ltd|Tablet and pestle therefor|
TWI589313B|2010-01-05|2017-07-01|麥可朵斯斯若波特公司|Pharmaceutical delivery package and inhaler|
US8383135B2|2010-12-03|2013-02-26|Richard C. Fuisz|Solid dosage form that promotes reliable oral, esophageal and GI transit|
GB201520007D0|2015-11-12|2015-12-30|Sensidose Ab|Compacted powder|
EP3431079A4|2016-03-15|2019-11-06|Astellas Pharma Inc.|Tablet|
JP2020019750A|2018-08-03|2020-02-06|株式会社ダイセル|Thin tablet, thin tablet manufacturing method, and thin tablet manufacturing apparatus|
JP2020026307A|2018-08-17|2020-02-20|株式会社ダイセル|Package, tablet-containing package, manufacturing method for storage member of package, and apparatus for manufacturing storage member of package|
法律状态:
优先权:
申请号 | 申请日 | 专利标题
GB8038993|1980-12-05|
GB8112987|1981-04-28|
[返回顶部]